Ethylene Oxide (EtO) Emissions Investigation

South Coast AQMD began investigating facilities that emit Ethylene Oxide (EtO) in March 2022, following the U.S. Environmental Protection Agency’s (U.S. EPA) reconsideration of the potential toxicity of EtO. U.S. EPA has recently been collecting new information about emissions from facilities that handle EtO throughout the country.

EtO sterilization and aeration facilities are subject to local, state, and federal regulations. South Coast AQMD Rule 1405 (PDF) - Control of Ethylene Oxide and Chlorofluorocarbon Emissions from Sterilization or Fumigation Processes reduces emissions of EtO from sterilization operations and has emission requirements that are more stringent than federal regulations.

South Coast AQMD is taking action to identify sources and reduce emissions. These actions include:

  • Air monitoring efforts at the facilities and near the surrounding community.

  • Proposition 65 Notice disclosure if applicable.

  • A complete investigation into the facilities’ equipment and compliance with South Coast AQMD rules, regulations and permit requirements.

  • Evaluation of immediate actions to be taken by the facilities to reduce leaks or fugitive emissions, including leak and source testing.

  • Begin rulemaking that will result in stricter requirements for EtO emissions from sterilization facilities.

About Ethylene Oxide

EtO is a flammable, colorless gas used in many industries to make products including antifreeze, textiles, solvents, detergents, and adhesives. Ethylene oxide also is used to sterilize medical equipment, which is the primary activity at Sterigenics. Exposure to EtO can irritate the eyes and respiratory system and damage the nervous system. Short-term exposure to EtO may cause headaches, weakness, nausea, vomiting, diarrhea, difficulty breathing, eye and skin burns, and reproductive effects. Long-term exposure to EtO over a number of years increases the risk of certain cancers including lymphoid cancer and, for females, breast cancer.

Ongoing Investigations

South Coast AQMD is investigating EtO emissions from the following facilities.

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South Coast Air Quality Management District

21865 Copley Dr, Diamond Bar, CA 91765


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